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    Y38F2AR.12 5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189679, updated on 2-Nov-2024

    Summary

    Official Symbol
    Y38F2AR.12
    Official Full Name
    5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein
    Primary source
    WormBase:WBGene00021430
    Locus tag
    CELE_Y38F2AR.12
    See related
    AllianceGenome:WB:WBGene00021430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 5-oxoprolinase (ATP-hydrolyzing) activity. Predicted to be involved in glutathione metabolic process. Predicted to be active in cytosol. Orthologous to human OPLAH (5-oxoprolinase, ATP-hydrolysing). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See Y38F2AR.12 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    14
    Sequence:
    Chromosome: IV; NC_003282.8 (2399484..2412420, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Protein kinase domain-containing protein;Tudor domain-containing protein Neighboring gene ncRNA Neighboring gene Major sperm protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 5-oxoprolinase (ATP-hydrolyzing) activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    5-oxoprolinase;Hydantoinase B/oxoprolinase domain-containing protein
    NP_001076725.2
    • Confirmed by transcript evidence
    NP_001294530.1
    • Confirmed by transcript evidence
    NP_001379804.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      2399484..2412420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001083256.4NP_001076725.2  5-oxoprolinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001076725.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A9S2
      Conserved Domains (1) summary
      PLN02666
      Location:11255
      PLN02666; 5-oxoprolinase
    2. NM_001392265.1NP_001379804.1  Hydantoinase B/oxoprolinase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86FM9
      Conserved Domains (1) summary
      PLN02666
      Location:23514
      PLN02666; 5-oxoprolinase
    3. NM_001307601.3NP_001294530.1  5-oxoprolinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294530.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMK1
      Conserved Domains (1) summary
      PLN02666
      Location:1941
      PLN02666; 5-oxoprolinase