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    C07B5.4 PH domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182361, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C07B5.4
    Official Full Name
    PH domain-containing protein
    Primary source
    WormBase:WBGene00007409
    Locus tag
    CELE_C07B5.4
    See related
    AllianceGenome:WB:WBGene00007409
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in actomyosin contractile ring assembly; mitotic cytokinesis; and septin ring organization. Predicted to be active in actomyosin contractile ring. Orthologous to several human genes including RTKN2 (rhotekin 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C07B5.4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (9529660..9536631)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene FLYWCH-type domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in septin ring organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in actomyosin contractile ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PH domain-containing protein
    NP_001024370.1
    • Confirmed by transcript evidence
    NP_001024371.2
    • Confirmed by transcript evidence
    NP_001382743.1
    • Confirmed by transcript evidence
    NP_001382744.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      9529660..9536631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001029199.7 → NP_001024370.1  PH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024370.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17777
      Conserved Domains (2) summary
      pfam00169
      Location:241 → 340
      PH; PH domain
      pfam08174
      Location:59 → 201
      Anillin; Cell division protein anillin

    2. NM_001395789.1 → NP_001382743.1  PH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8D9IA70
      Conserved Domains (1) summary
      cl17171
      Location:265 → 339
      PH-like; Pleckstrin homology-like domain

    3. NM_001029200.7 → NP_001024371.2  PH domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001024371.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5WRQ4
      Conserved Domains (2) summary
      pfam00169
      Location:196 → 295
      PH; PH domain
      pfam08174
      Location:14 → 156
      Anillin; Cell division protein anillin

    4. NM_001395790.1 → NP_001382744.1  PH domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A8D9I6W5
      Conserved Domains (1) summary
      cl17171
      Location:220 → 294
      PH-like; Pleckstrin homology-like domain
    Nucleotide Protein
    Heading Accession and Version

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