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    C31H5.6 BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein;BAAT/acyl-CoA thioester hydrolase protein [ Caenorhabditis elegans ]

    Gene ID: 172725, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C31H5.6
    Official Full Name
    BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein;BAAT/acyl-CoA thioester hydrolase protein
    Primary source
    WormBase:WBGene00007857
    Locus tag
    CELE_C31H5.6
    See related
    AllianceGenome:WB:WBGene00007857
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Human ortholog(s) of this gene implicated in disease of metabolism. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C31H5.6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (9043321..9046575, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene DUF4440 domain-containing protein Neighboring gene Nematode Specific Peptide family, group A Neighboring gene Uncharacterized protein Neighboring gene Homogentisate 1,2-dioxygenase Neighboring gene tRNA-Asn Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Tan D, et al. Elife, 2016 Mar 8. PMID 26952210, Free PMC Article
    2. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein;BAAT/acyl-CoA thioester hydrolase protein
    NP_001129757.1
    • Confirmed by transcript evidence
    NP_492431.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9043321..9046575 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060030.7 → NP_492431.2  BAAT/acyl-CoA thioester hydrolase protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492431.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3WFZ3
      Conserved Domains (2) summary
      pfam04775
      Location:15 → 131
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      cl21494
      Location:198 → 406
      Abhydrolase; alpha/beta hydrolases

    2. NM_001136285.4 → NP_001129757.1  BAAT/Acyl-CoA thioester hydrolase C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001129757.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3WFZ4
      Conserved Domains (2) summary
      pfam04775
      Location:1 → 57
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      cl21494
      Location:124 → 332
      Abhydrolase; alpha/beta hydrolases
    Nucleotide Protein
    Heading Accession and Version

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