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    maco-1 Macoilin [ Caenorhabditis elegans ]

    Gene ID: 183963, updated on 2-Nov-2024

    Summary

    Official Symbol
    maco-1
    Official Full Name
    Macoilin
    Primary source
    WormBase:WBGene00017066
    Locus tag
    CELE_D2092.5
    See related
    AllianceGenome:WB:WBGene00017066
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable microtubule binding activity. Involved in chemotaxis; neuronal signal transduction; and thermotaxis. Located in neuronal cell body; nuclear envelope; and rough endoplasmic reticulum. Is expressed in epithelial cell; muscle cell; and nervous system. Orthologous to human MACO1 (macoilin 1). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See maco-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    13
    Sequence:
    Chromosome: I; NC_003279.8 (6598982..6607520, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene SH2 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Thioredoxin domain-containing protein Neighboring gene ncRNA

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in locomotion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuronal signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neuronal signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuronal signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in thermotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in rough endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in rough endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in rough endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Macoilin
    NP_491902.4
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6598982..6607520 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059501.7NP_491902.4  Macoilin [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491902.4

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91193
      Conserved Domains (1) summary
      pfam09726
      Location:38707
      Macoilin; Transmembrane protein