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    Y39A1A.21 ATP synthase subunit C lysine N-methyltransferase [ Caenorhabditis elegans ]

    Gene ID: 176493, updated on 9-Dec-2024

    Summary

    Official Symbol
    Y39A1A.21
    Official Full Name
    ATP synthase subunit C lysine N-methyltransferase
    Primary source
    WormBase:WBGene00012658
    Locus tag
    CELE_Y39A1A.21
    See related
    AllianceGenome:WB:WBGene00012658
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine trimethylation; positive regulation of proton-transporting ATP synthase activity, rotational mechanism; and regulation of mitochondrial ATP synthesis coupled proton transport. Predicted to be active in mitochondrion. Orthologous to several human genes including ATPSCKMT (ATP synthase c subunit lysine N-methyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y39A1A.21 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (10700667..10707022, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Flavin-containing monooxygenase Neighboring gene Uncharacterized protein Neighboring gene Xenotropic and polytropic retrovirus receptor 1 homolog Neighboring gene Mitochondrial Ribosomal Protein, Large Neighboring gene N-acetylgalactosaminide beta-1,3-galactosyltransferase Neighboring gene Protein phosphatase

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables histone methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-lysine N-methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein-lysine N-methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein-lysine N-methyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    ATP synthase subunit C lysine N-methyltransferase
    NP_001299903.1
    • Confirmed by transcript evidence
    NP_001379034.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10700667..10707022 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001312974.3NP_001299903.1  ATP synthase subunit C lysine N-methyltransferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3ARX5
    2. NM_001392205.1NP_001379034.1  ATP synthase subunit C lysine N-methyltransferase [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XX11
      Conserved Domains (1) summary
      cl17173
      Location:69111
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    RNA

    1. NR_002375.1 RNA Sequence

      Status: REVIEWED