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    ipla-4 phospholipase A2 [ Caenorhabditis elegans ]

    Gene ID: 171937, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ipla-4
    Official Full Name
    phospholipase A2
    Primary source
    WormBase:WBGene00017026
    Locus tag
    CELE_D1037.5
    See related
    AllianceGenome:WB:WBGene00017026
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in lipid metabolic process. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ipla-4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    11
    Sequence:
    Chromosome: I; NC_003279.8 (3690145..3694021, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ferritin Neighboring gene Ras-related protein Rab-8A Neighboring gene Protein SON Neighboring gene DNA mismatch repair proteins mutS family domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling. Schmeisser S, et al. Cell Rep, 2019 Dec 24. PMID 31875559
    2. Roles of acidic phospholipids and nucleotides in regulating membrane binding and activity of a calcium-independent phospholipase A2 isoform. Morrison K, et al. J Biol Chem, 2012 Nov 9. PMID 23007400, Free PMC Article
    3. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    phospholipase A2
    NP_491201.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3690145..3694021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058800.4 → NP_491201.3  phospholipase A2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491201.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TYS0
      Conserved Domains (4) summary
      cd07212
      Location:176 → 502
      Pat_PNPLA9; Patatin-like phospholipase domain containing protein 9
      cd00204
      Location:55 → 123
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam13637
      Location:52 → 105
      Ank_4; Ankyrin repeats (many copies)
      sd00045
      Location:53 → 82
      ANK; ANK repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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