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    tkt-1 transketolase [ Caenorhabditis elegans ]

    Gene ID: 177906, updated on 9-Dec-2024

    Summary

    Official Symbol
    tkt-1
    Official Full Name
    transketolase
    Primary source
    WormBase:WBGene00008506
    Locus tag
    CELE_F01G10.1
    See related
    AllianceGenome:WB:WBGene00008506
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable thiamine pyrophosphate binding activity and transketolase activity. Predicted to be located in mitochondrion. Is expressed in intestine; pharynx; and reproductive system. Orthologous to several human genes including TKT (transketolase) and TKTL2 (transketolase like 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See tkt-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (10243612..10245707)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Enoyl-CoA Hydratase Neighboring gene Lipase Neighboring gene BPI2 domain-containing protein Neighboring gene Smad-related protein daf-14 Neighboring gene Ground-like domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiamine pyrophosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transketolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transketolase
    NP_501878.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      10243612..10245707
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069477.5NP_501878.1  transketolase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501878.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O17759
      Conserved Domains (1) summary
      PRK05899
      Location:9615
      PRK05899; transketolase; Reviewed