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    slc-17.1 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181777, updated on 14-Nov-2024

    Summary

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    Official Symbol
    slc-17.1
    Official Full Name
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00022647
    Locus tag
    CELE_ZK54.1
    See related
    AllianceGenome:WB:WBGene00022647
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in monoatomic anion transport. Located in sarcoplasmic reticulum. Human ortholog(s) of this gene implicated in sialuria. Orthologous to human SLC17A5 (solute carrier family 17 member 5). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See slc-17.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    11
    Sequence:
    Chromosome: X; NC_003284.9 (17460778..17464901, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Myosin regulatory light chain 1 Neighboring gene MFS transporter Neighboring gene Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sarcoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_001041300.1
    • Confirmed by transcript evidence
    NP_001041301.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      17460778..17464901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047836.7 → NP_001041301.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041301.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PJ91
      Conserved Domains (1) summary
      cd17318
      Location:37 → 455
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters

    2. NM_001047835.5 → NP_001041300.1  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041300.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23514
      Conserved Domains (1) summary
      cd17318
      Location:42 → 460
      MFS_SLC17; Solute carrier 17 (SLC17) family of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version

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