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    ddo-3 D-aspartate oxidase 3 [ Caenorhabditis elegans ]

    Gene ID: 184746, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ddo-3
    Official Full Name
    D-aspartate oxidase 3
    Primary source
    WormBase:WBGene00017648
    Locus tag
    CELE_F20H11.5
    See related
    AllianceGenome:WB:WBGene00017648
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable D-aspartate oxidase activity and FAD binding activity. Predicted to be involved in D-amino acid catabolic process. Located in extracellular region. Is expressed in several structures, including coelomocyte; eggshell; excretory socket cell; head mesodermal cell; and reproductive system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ddo-3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (6587864..6589398)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Zinc finger protein 263 Neighboring gene AcetylCholine Receptor Neighboring gene Differentially expressed in FDCP 8 homolog Neighboring gene ncRNA Neighboring gene Protein strawberry notch homolog

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Secreted d-aspartate oxidase functions in C. elegans reproduction and development. Saitoh Y, et al. FEBS J, 2019 Jan. PMID 30387556
    2. Biochemical characterization of d-aspartate oxidase from Caenorhabditis elegans: its potential use in the determination of free d-glutamate in biological samples. Katane M, et al. Biochim Biophys Acta Proteins Proteom, 2020 Aug. PMID 32376478
    3. Spatiotemporal localization of D-amino acid oxidase and D-aspartate oxidases during development in Caenorhabditis elegans. Saitoh Y, et al. Mol Cell Biol, 2012 May. PMID 22393259, Free PMC Article
    4. Comparative characterization of three D-aspartate oxidases and one D-amino acid oxidase from Caenorhabditis elegans. Katane M, et al. Chem Biodivers, 2010 Jun. PMID 20564561
    5. Caenorhabditis elegans has two genes encoding functional d-aspartate oxidases. Katane M, et al. FEBS J, 2007 Jan. PMID 17140416

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables D-amino-acid oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables D-amino-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-aspartate oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-aspartate oxidase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables D-glutamate oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FAD binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in D-amino acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in D-amino acid catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in D-amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    D-aspartate oxidase 3
    NP_498453.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6587864..6589398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066052.5 → NP_498453.1  D-aspartate oxidase 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498453.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01739, Q08I98
      Conserved Domains (1) summary
      pfam01266
      Location:19 → 351
      DAO; FAD dependent oxidoreductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O01739.1

    Gene LinkOut

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