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    ucr-2.1 Peptidase_M16 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181374, updated on 2-Nov-2024

    Summary

    Official Symbol
    ucr-2.1
    Official Full Name
    Peptidase_M16 domain-containing protein
    Primary source
    WormBase:WBGene00012158
    Locus tag
    CELE_VW06B3R.1
    See related
    AllianceGenome:WB:WBGene00012158
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable metal ion binding activity. Predicted to be active in mitochondrion. Is expressed in gonad. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 5. Orthologous to human UQCRC2 (ubiquinol-cytochrome c reductase core protein 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See ucr-2.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    9
    Sequence:
    Chromosome: X; NC_003284.9 (12018429..12021206)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Nicotinamide-nucleotide adenylyltransferase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Peptidase_M16 domain-containing protein
    NP_001379251.1
    • Confirmed by transcript evidence
    NP_510012.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      12018429..12021206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077611.6NP_510012.2  Peptidase_M16 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510012.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDD1
      Conserved Domains (3) summary
      COG0612
      Location:26404
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:49189
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:195347
      Peptidase_M16_C; Peptidase M16 inactive domain
    2. NM_001392857.1NP_001379251.1  Peptidase_M16 domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ED31
      Conserved Domains (1) summary
      COG0612
      Location:12390
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]