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    F20H11.4 Protein-tyrosine phosphatase [ Caenorhabditis elegans ]

    Gene ID: 175937, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F20H11.4
    Official Full Name
    Protein-tyrosine phosphatase
    Primary source
    WormBase:WBGene00017647
    Locus tag
    CELE_F20H11.4
    See related
    AllianceGenome:WB:WBGene00017647
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in motor neuron axon guidance and signal transduction. Is expressed in nervous system and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F20H11.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (6608622..6610455)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Protein strawberry notch homolog Neighboring gene Malate dehydrogenase, mitochondrial Neighboring gene Serpentine Receptor, class T Neighboring gene Carboxypeptidase Neighboring gene Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in motor neuron axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein-tyrosine phosphatase
    NP_498458.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6608622..6610455
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066057.4 → NP_498458.1  Protein-tyrosine phosphatase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498458.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01736
      Conserved Domains (2) summary
      cd00047
      Location:144 → 375
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
      pfam00102
      Location:142 → 375
      Y_phosphatase; Protein-tyrosine phosphatase
    Nucleotide Protein
    Heading Accession and Version

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