U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    gpa-10 Guanine nucleotide-binding protein alpha-10 subunit [ Caenorhabditis elegans ]

    Gene ID: 179075, updated on 2-Nov-2024

    Summary

    Official Symbol
    gpa-10
    Official Full Name
    Guanine nucleotide-binding protein alpha-10 subunit
    Primary source
    WormBase:WBGene00001672
    Locus tag
    CELE_C55H1.2
    See related
    AllianceGenome:WB:WBGene00001672
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Involved in short-term memory. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in intestine; nervous system; and reproductive system. [provided by Alliance of Genome Resources, Nov 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See gpa-10 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    9
    Sequence:
    Chromosome: V; NC_003283.11 (6852521..6854811, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene FMRFamide peptide receptor frpr-18

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta/gamma-subunit complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables guanyl nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in short-term memory IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Guanine nucleotide-binding protein alpha-10 subunit
    NP_504745.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      6852521..6854811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072344.3NP_504745.1  Guanine nucleotide-binding protein alpha-10 subunit [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504745.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q18873, Q9BIG4
      Conserved Domains (2) summary
      cd00066
      Location:39350
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
      smart00275
      Location:17354
      G_alpha; G protein alpha subunit