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    SRL2 Srl2p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850771, updated on 2-Nov-2024

    Summary

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    Official Symbol
    SRL2
    Official Full Name
    Srl2p
    Primary source
    SGD:S000004072
    Locus tag
    YLR082C
    See related
    AllianceGenome:SGD:S000004072; FungiDB:YLR082C; VEuPathDB:YLR082C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in nucleobase-containing compound metabolic process. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See SRL2 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (292394..293572, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Emp46p Neighboring gene galactose permease GAL2 Neighboring gene Emp70p Neighboring gene Rax2p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway. Desany BA, et al. Genes Dev, 1998 Sep 15. PMID 9744871, Free PMC Article
    2. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. Srikumar T, et al. J Cell Biol, 2013 Apr 1. PMID 23547032, Free PMC Article
    3. Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Fromont-Racine M, et al. Yeast, 2000 Jun 30. PMID 10900456, Free PMC Article
    4. Multi-signal regulation of the GSK-3β homolog Rim11 controls meiosis entry in budding yeast. Kociemba J, et al. EMBO J, 2024 Aug. PMID 38886580, Free PMC Article
    5. Meiosis-specific cohesin component, Rec8, promotes the localization of Mps3 SUN domain protein on the nuclear envelope. Bommi JR, et al. Genes Cells, 2019 Jan. PMID 30417519

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in nucleobase-containing compound metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Srl2p
    NP_013183.1
    • hypothetical protein; overexpression suppresses the lethality caused by a rad53 null mutation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      292394..293572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181969.1 → NP_013183.1  TPA: Srl2p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013183.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY82, Q12020
      UniProtKB/TrEMBL
      G2WIS3, N1NZ67
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12020.1

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