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    RGR1 Rgr1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850760, updated on 14-Nov-2024

    Summary

    Official Symbol
    RGR1
    Official Full Name
    Rgr1p
    Primary source
    SGD:S000004061
    Locus tag
    YLR071C
    See related
    AllianceGenome:SGD:S000004061; FungiDB:YLR071C; VEuPathDB:YLR071C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    MED14
    Summary
    Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and TFIIB-class transcription factor binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Part of core mediator complex. Orthologous to human MED14 (mediator complex subunit 14). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See RGR1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (275378..278626, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Mef1p Neighboring gene D-xylulose reductase XYL2 Neighboring gene Lam6p Neighboring gene Rfu1p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables TFIIB-class transcription factor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of core mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Rgr1p
    NP_013172.1
    • Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      275378..278626 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181958.1NP_013172.1  TPA: Rgr1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013172.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY72, P19263, Q07999
      UniProtKB/TrEMBL
      G2WIR3
      Conserved Domains (1) summary
      pfam08638
      Location:89292
      Med14; Mediator complex subunit MED14