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    [ Saccharomyces cerevisiae S288C ]

    Gene ID: 2827706, updated on 9-Dec-2024

    Summary

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    Primary source
    SGD:S000003940
    Locus tag
    YLL017W
    See related
    AllianceGenome:SGD:S000003940; FungiDB:YLL017W; VEuPathDB:YLL017W
    Gene type
    pseudo
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SDC25
    Summary
    Predicted to be involved in cell division. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XII
    Sequence:
    Chromosome: XII; NC_001144.5 (112234..112545)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Cox19p Neighboring gene aspartate--tRNA ligase DPS1 Neighboring gene pseudo Neighboring gene ATP-binding cassette bilirubin transporter BPT1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RAS residues that are distant from the GDP binding site play a critical role in dissociation factor-stimulated release of GDP. Verrotti AC, et al. EMBO J, 1992 Aug. PMID 1639059, Free PMC Article
    2. Enhancement of the GDP-GTP exchange of RAS proteins by the carboxyl-terminal domain of SCD25. Créchet JB, et al. Science, 1990 May 18. PMID 2188363
    3. The C-terminal part of a gene partially homologous to CDC 25 gene suppresses the cdc25-5 mutation in Saccharomyces cerevisiae. Boy-Marcotte E, et al. Gene, 1989 Apr 15. PMID 2545538
    4. The cellular content of Cdc25p, the Ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box. Kaplon T, et al. J Biol Chem, 1995 Sep 1. PMID 7657656
    5. The Saccharomyces cerevisiae gene product SDC25 C-domain functions as an oncoprotein in NIH3T3 cells. Barlat I, et al. Oncogene, 1993 Jan. PMID 7999142

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • Non-essential Ras guanine nucleotide exchange factor (GEF); localized to the membrane; expressed in poor nutrient conditions and on nonfermentable carbon sources; contains a stop codon in S288C, full-length gene includes YLL016W; SDC25 has a paralog, CDC25, that arose from the whole genome duplication

    Gene Ontology Provided by SGD

    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  

    Gene LinkOut

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    Other Literature Sources
    Research Materials