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    CG17883 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355139, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG17883provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040005
    Locus tag
    Dmel_CG17883
    See related
    AllianceGenome:FB:FBgn0040005
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG40289; Dmel\CG17883
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endoplasmic reticulum. Is expressed in adult head and organism. Human ortholog(s) of this gene implicated in Warburg micro syndrome 4. Orthologous to human TBC1D20 (TBC1 domain family member 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG17883 in Genome Data Viewer
    Location:
    41B3-41B3; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (4671853..4673639)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (559358..561144)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene downstream non-coding target of Rpd3 and Loco Neighboring gene uncharacterized protein Neighboring gene Nipped-B Neighboring gene long non-coding RNA:CR45471 Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    • Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG17883-PA
    CG17883-PB
    CG17883-PC
    CG17883-PD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      4671853..4673639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001042984.2NP_001036449.1  uncharacterized protein Dmel_CG17883, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036449.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5LJQ4
      Conserved Domains (1) summary
      pfam00566
      Location:91260
      RabGAP-TBC; Rab-GTPase-TBC domain
    2. NM_001042983.2NP_001036448.1  uncharacterized protein Dmel_CG17883, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036448.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7PLI1, Q9W5H8
      Conserved Domains (1) summary
      pfam00566
      Location:91260
      RabGAP-TBC; Rab-GTPase-TBC domain
    3. NM_001273772.1NP_001260701.1  uncharacterized protein Dmel_CG17883, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEC2
      Conserved Domains (1) summary
      pfam00566
      Location:91260
      RabGAP-TBC; Rab-GTPase-TBC domain
    4. NM_001273773.1NP_001260702.1  uncharacterized protein Dmel_CG17883, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260702.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4KEH8
      Conserved Domains (1) summary
      pfam00566
      Location:91260
      RabGAP-TBC; Rab-GTPase-TBC domain