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    Ent3 Equilibrative nucleoside transporter 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39461, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ent3provided by FlyBase
    Official Full Name
    Equilibrative nucleoside transporter 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0036319
    Locus tag
    Dmel_CG11010
    See related
    AllianceGenome:FB:FBgn0036319
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11010; Dmel\CG11010; DmEnt3; DmENT3; ent3; ENT3
    Summary
    Predicted to enable monoamine transmembrane transporter activity and nucleoside transmembrane transporter activity. Predicted to be involved in nucleoside transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in adult head. Orthologous to human SLC29A4 (solute carrier family 29 member 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Ent3 in Genome Data Viewer
    Location:
    69E6-69E6; 3-39 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12853646..12857428)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12846746..12850528)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene WW domain binding protein 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables monoamine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nucleoside transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleoside transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in nucleoside transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleoside transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in nucleoside transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    equilibrative nucleoside transporter 3
    Names
    CG11010-PA
    CG11010-PB
    CG11010-PC
    Ent3-PA
    Ent3-PB
    Ent3-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12853646..12857428
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300123.1NP_001287052.1  equilibrative nucleoside transporter 3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287052.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961M5, Q9VU20
      Conserved Domains (1) summary
      cl15430
      Location:60529
      Nucleoside_tran; Nucleoside transporter
    2. NM_001274859.2NP_001261788.1  equilibrative nucleoside transporter 3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261788.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PI48, Q961M5
      Conserved Domains (1) summary
      cl15430
      Location:60528
      Nucleoside_tran; Nucleoside transporter
    3. NM_140351.3NP_648608.2  equilibrative nucleoside transporter 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648608.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q961M5, Q9VU20
      Related
      FBpp0075667
      Conserved Domains (1) summary
      cl15430
      Location:60529
      Nucleoside_tran; Nucleoside transporter