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    CG6656 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42576, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG6656provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038912
    Locus tag
    Dmel_CG6656
    See related
    AllianceGenome:FB:FBgn0038912
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG6656
    Summary
    Predicted to enable acid phosphatase activity. Predicted to be located in extracellular exosome and nucleus. Is expressed in adult head; eye; and photoreceptor neurons. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 1J and prostate cancer. Orthologous to human ACP2 (acid phosphatase 2, lysosomal); ACP3 (acid phosphatase 3); and ACP4 (acid phosphatase 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG6656 in Genome Data Viewer
    Location:
    93F14-93F14; 3-73 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (21875293..21877788)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17701015..17703510)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45046 Neighboring gene uncharacterized protein Neighboring gene delta-1-Pyrroline-5-carboxylate dehydrogenase 2 Neighboring gene uncharacterized protein Neighboring gene female-specific independent of transformer

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Ski2-family helicase Obelus regulates Crumbs alternative splicing and cell polarity. Vichas A, et al. J Cell Biol, 2015 Dec 7. PMID 26644515, Free PMC Article
    2. CULD is required for rhodopsin and TRPL channel endocytic trafficking and survival of photoreceptor cells. Xu Y, et al. J Cell Sci, 2016 Jan 15. PMID 26598556, Free PMC Article
    3. Vitamin A deficiency affects gene expression in the Drosophila melanogaster head. Dewett D, et al. G3 (Bethesda), 2021 Oct 19. PMID 34849795, Free PMC Article
    4. Isolation of mRNA from specific tissues of Drosophila by mRNA tagging. Yang Z, et al. Nucleic Acids Res, 2005 Oct 4. PMID 16204451, Free PMC Article
    5. A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen. Xu H, et al. EMBO J, 2004 Feb 25. PMID 14963491, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acid phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG6656-PA
    NP_650991.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21875293..21877788
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142734.2 → NP_650991.1  uncharacterized protein Dmel_CG6656 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650991.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VD68
      Related
      FBpp0083537
      Conserved Domains (1) summary
      cd07061
      Location:41 → 344
      HP_HAP_like; Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VD68 Q9VD68

    Gene LinkOut

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