betaTub97EF beta-Tubulin at 97EF [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: betaTub97EFprovided by FlyBase
Official Full Name: beta-Tubulin at 97EFprovided by FlyBase
Primary source: FLYBASE:FBgn0003890
Locus tag: Dmel_CG4869
See related: AllianceGenome:FB:FBgn0003890
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: 4t; B4t; BETA 98B; beta-tub; beta-Tub; beta-Tub97EF; beta4; beta4t; beta97F; betaTub4; betaTub98BC; betaTub98C; betatubulin; CG4869; Dmbeta4; Dmel\CG4869; DTB1; T; Tub; Tub2C
Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in imaginal disc fusion, thorax closure. Predicted to be active in cytoplasm and microtubule. Is expressed in several structures, including adult glial cell; adult head; adult heart; neuromuscular junction; and spermatozoon. Orthologous to human TUBB8 (tubulin beta 8 class VIII) and TUBB8B (tubulin beta 8B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (27967008..27988384, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (23792730..23814106, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables structural constituent of cytoskeleton	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of cytoskeleton	IEA Inferred from Electronic Annotation more info
enables structural constituent of cytoskeleton	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in imaginal disc fusion, thorax closure	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule cytoskeleton organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in microtubule-based process	IEA Inferred from Electronic Annotation more info
involved_in mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in microtubule	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Names: Beta4-tubulin; CG4869-PB; CG4869-PC; beta tubulin; beta-Tubulin; beta-Tubulin 97EF; beta4 tubulin; betaTub97EF-PB; betaTub97EF-PC; betatubulin; tubulin

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The following sections contain reference sequences that belong to a specific genome build. Explain