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    CG7420 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33332, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG7420provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031344
    Locus tag
    Dmel_CG7420
    See related
    AllianceGenome:FB:FBgn0031344
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7420
    Summary
    Predicted to be involved in regulation of mitotic cell cycle and regulation of mitotic spindle assembly. Predicted to be active in cytoplasm. Orthologous to human SERGEF (secretion regulating guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7420 in Genome Data Viewer
    Location:
    22A2-22A2; 2-3 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (1500784..1502904, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (1500784..1502904, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44064 Neighboring gene uncharacterized protein Neighboring gene halo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. MicroRNA miR-308 regulates dMyc through a negative feedback loop in Drosophila. Daneshvar K, et al. Biol Open, 2013 Jan 15. PMID 23336071, Free PMC Article
    2. Dynamics of Dark-Fly Genome Under Environmental Selections. Izutsu M, et al. G3 (Bethesda), 2015 Dec 4. PMID 26637434, Free PMC Article
    3. The nucleosome remodeling factor ISWI functionally interacts with an evolutionarily conserved network of cellular factors. Arancio W, et al. Genetics, 2010 May. PMID 20194965, Free PMC Article
    4. A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience. Evans CJ, et al. G3 (Bethesda), 2021 Jan 18. PMID 33561251, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7420-PA
    CG7420-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      1500784..1502904 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001272942.2 → NP_001259871.1  uncharacterized protein Dmel_CG7420, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259871.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PAZ8
      Conserved Domains (2) summary
      pfam00415
      Location:55 → 107
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:256 → 285
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat

    2. NM_134758.4 → NP_608602.1  uncharacterized protein Dmel_CG7420, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608602.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95RM1, Q9VQ16
      Related
      FBpp0077598
      Conserved Domains (2) summary
      pfam00415
      Location:328 → 373
      RCC1; Regulator of chromosome condensation (RCC1) repeat
      pfam13540
      Location:256 → 285
      RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PAZ8 M9PAZ8
    Q9VQ16 Q9VQ16

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