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    Gar1 Gar1 ribonucleoprotein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37397, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gar1provided by FlyBase
    Official Full Name
    Gar1 ribonucleoproteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011824
    Locus tag
    Dmel_CG4038
    See related
    AllianceGenome:FB:FBgn0011824
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-Pen101; CG4038; CG4038-PA; dGAR1; Dmel\CG4038; GAR1; GCR 101; GCR101; GCR101 SnRNP; Pen101
    Summary
    Predicted to enable box H/ACA snoRNA binding activity. Predicted to be involved in snoRNA guided rRNA pseudouridine synthesis. Located in nucleolus and nucleoplasm. Is expressed in several structures, including adult brain cell body rind; adult fat body; embryonic/larval midgut primordium; larval muscle cell; and mesoderm. Orthologous to human GAR1 (GAR1 ribonucleoprotein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Gar1 in Genome Data Viewer
    Location:
    57B20-57B20; 2-92 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21095958..21097305, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (16983463..16984810, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR44704 Neighboring gene uncharacterized protein Neighboring gene Trehalase Neighboring gene Rabaptin-5 Neighboring gene uncharacterized protein Neighboring gene king tubby Neighboring gene uncharacterized protein Neighboring gene Transmembrane O-mannosyltransferase targeting cadherins 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of a distinct genomic domain in Drosophila: comparative analysis of the dot chromosome in Drosophila melanogaster and Drosophila virilis. Leung W, et al. Genetics, 2010 Aug. PMID 20479145, Free PMC Article
    2. Temporal and sequential order of nonoverlapping gene networks unraveled in mated female Drosophila. Pasquier C, et al. Life Sci Alliance, 2022 Feb. PMID 34844981, Free PMC Article
    3. Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster. Thomas C, et al. Dev Biol, 2014 Jan 1. PMID 24104056, Free PMC Article
    4. PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth. Ciurciu A, et al. PLoS Genet, 2013 Oct. PMID 24204300, Free PMC Article
    5. Native purification of protein and RNA-protein complexes using a novel affinity procedure. Kroiss M, et al. Fly (Austin), 2009 Jul-Sep. PMID 19690462

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables box H/ACA snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in rRNA pseudouridine synthesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in snoRNA guided rRNA pseudouridine synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of box H/ACA snoRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of box H/ACA snoRNP complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleolus HDA PubMed 
    located_in nucleoplasm HDA PubMed 
    part_of sno(s)RNA-containing ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Gar1 ribonucleoprotein
    Names
    CG4038-PA
    Gar1-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21095958..21097305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057695.4 → NP_477043.1  Gar1 ribonucleoprotein [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477043.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24345, Q7KVQ0, Q86R95, Q9W2L8
      UniProtKB/TrEMBL
      A8E6K0
      Related
      FBpp0071562
      Conserved Domains (1) summary
      pfam04410
      Location:61 → 162
      Gar1; Gar1/Naf1 RNA binding region
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KVQ0.1 Q7KVQ0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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