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    CG12520 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39466, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12520provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036324
    Locus tag
    Dmel_CG12520
    See related
    AllianceGenome:FB:FBgn0036324
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG12520; FBgn0036324
    Summary
    Predicted to enable SCF ubiquitin ligase complex binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12520 in Genome Data Viewer
    Location:
    69F1-69F1; 3-39 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12901247..12902737, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12894347..12895837, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Some novel intron positions in conserved Drosophila genes are caused by intron sliding or tandem duplication. Lehmann J, et al. BMC Evol Biol, 2010 May 26. PMID 20500887, Free PMC Article
    2. Molecular profiling of stem cell-like female germ line cells in Drosophila delineates networks important for stemness and differentiation. Tiwari MD, et al. Biol Open, 2019 Nov 12. PMID 31649115, Free PMC Article
    3. A systematic phenotypic screen of F-box genes through a tissue-specific RNAi-based approach in Drosophila. Dui W, et al. J Genet Genomics, 2012 Aug 20. PMID 22884096
    4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    5. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables SCF ubiquitin ligase complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISM
    Inferred from Sequence Model
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12520-PB
    CG12520-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12901247..12902737 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104126.2 → NP_001097596.1  uncharacterized protein Dmel_CG12520, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097596.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU25
      Conserved Domains (1) summary
      smart00256
      Location:11 → 44
      FBOX; A Receptor for Ubiquitination Targets

    2. NM_001300124.1 → NP_001287053.1  uncharacterized protein Dmel_CG12520, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287053.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2J912
      Conserved Domains (1) summary
      smart00256
      Location:11 → 44
      FBOX; A Receptor for Ubiquitination Targets
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU25 Q9VU25
    X2J912 X2J912

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