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    CG14174 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39139, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG14174provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036036
    Locus tag
    Dmel_CG14174
    See related
    AllianceGenome:FB:FBgn0036036
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG14174
    Summary
    Predicted to be involved in positive regulation of Notch signaling pathway. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in anauxetic dysplasia 3. Orthologous to human NEPRO (nucleolus and neural progenitor protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG14174 in Genome Data Viewer
    Location:
    67C5-67C5; 3-31 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (9719328..9720464)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (9712428..9713564)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene visgun Neighboring gene small non-coding RNA 838 Neighboring gene uncharacterized protein Neighboring gene nbs Neighboring gene deflated Neighboring gene N(alpha)-acetyltransferase 60

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Epigenetic telomere protection by Drosophila DNA damage response pathways. Oikemus SR, et al. PLoS Genet, 2006 May. PMID 16710445, Free PMC Article
    2. Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi. Neumüller RA, et al. Cell Stem Cell, 2011 May 6. PMID 21549331, Free PMC Article
    3. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    4. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    5. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in positive regulation of Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG14174-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      9719328..9720464
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140094.2 → NP_648351.1  uncharacterized protein Dmel_CG14174 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648351.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VT39, T2GGJ7
      Related
      FBpp0076131
      Conserved Domains (1) summary
      pfam14780
      Location:7 → 191
      DUF4477; Domain of unknown function (DUF4477)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T8U9 Q8T8U9
    Q9VT39 Q9VT39

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