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    CG12096 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32269, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG12096provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030457
    Locus tag
    Dmel_CG12096
    See related
    AllianceGenome:FB:FBgn0030457
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    12096; Dmel\CG12096; dS5b; S5b; S5b/PSMD5
    Summary
    Predicted to be involved in proteasome assembly. Is expressed in adult head and organism. Orthologous to human PSMD5 (proteasome 26S subunit, non-ATPase 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG12096 in Genome Data Viewer
    Location:
    11E1-11E1; 1-42 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (13159604..13162854)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (13053637..13056887)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Brahma associated protein 60kD Neighboring gene Leucine-rich repeat-containing G protein-coupled receptor 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of S5b/PSMD5 in proteasome inhibition caused by TNF-α/NFκB in higher eukaryotes. Shim SM, et al. Cell Rep, 2012 Sep 27. PMID 22921402
    2. Drosophila BAP60 is an essential component of the Brahma complex, required for gene activation and repression. Möller A, et al. J Mol Biol, 2005 Sep 16. PMID 16083904
    3. Proteasome regulation by ADP-ribosylation. Cho-Park PF, et al. Cell, 2013 Apr 25. PMID 23622245, Free PMC Article
    4. The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. Gurudatta BV, et al. Dev Biol, 2012 Sep 1. PMID 22743648, Free PMC Article
    5. A network of conserved damage survival pathways revealed by a genomic RNAi screen. Ravi D, et al. PLoS Genet, 2009 Jun. PMID 19543366, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in proteasome assembly IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG12096-PA
    CG12096-PB
    CG12096-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      13159604..13162854
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132634.4 → NP_572862.2  uncharacterized protein Dmel_CG12096, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572862.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
      UniProtKB/TrEMBL
      X2JBJ9
      Related
      FBpp0073558
      Conserved Domains (1) summary
      pfam10508
      Location:4 → 502
      Proteasom_PSMB; Proteasome non-ATPase 26S subunit

    2. NM_001298262.1 → NP_001285191.1  uncharacterized protein Dmel_CG12096, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285191.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
      UniProtKB/TrEMBL
      X2JBJ9
      Conserved Domains (1) summary
      pfam10508
      Location:4 → 502
      Proteasom_PSMB; Proteasome non-ATPase 26S subunit

    3. NM_001298261.1 → NP_001285190.1  uncharacterized protein Dmel_CG12096, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285190.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A9UNC9, Q7K0M3, Q8SZZ0, Q9VYG1
      UniProtKB/TrEMBL
      X2JBJ9
      Conserved Domains (1) summary
      pfam10508
      Location:4 → 502
      Proteasom_PSMB; Proteasome non-ATPase 26S subunit
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VYG1.3 Q9VYG1
    X2JBJ9 X2JBJ9

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