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    CG16952 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32546, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG16952provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030701
    Locus tag
    Dmel_CG16952
    See related
    AllianceGenome:FB:FBgn0030701
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG16952
    Summary
    Predicted to be involved in morphogenesis of a branching epithelium. Is expressed in central brain primordium; embryonic brain; larval ventral nerve cord; organism; and ventral nerve cord primordium. Orthologous to human BTBD7 (BTB domain containing 7). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG16952 in Genome Data Viewer
    Location:
    13F17-13F17; 1-52 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (15870183..15875607)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (15764216..15769640)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene G protein beta subunit 13F Neighboring gene Glyceraldehyde 3 phosphate dehydrogenase 2 Neighboring gene tay bridge Neighboring gene membrane steroid binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Tay bridge is a negative regulator of EGFR signalling and interacts with Erk and Mkp3 in the Drosophila melanogaster wing. Molnar C, et al. PLoS Genet, 2013. PMID 24348264, Free PMC Article
    2. Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila. Raza Q, et al. PLoS Genet, 2019 Feb. PMID 30763317, Free PMC Article
    3. Evolutionary Dynamics of Abundant Stop Codon Readthrough. Jungreis I, et al. Mol Biol Evol, 2016 Dec. PMID 27604222, Free PMC Article
    4. Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. Krauchunas AR, et al. Dev Biol, 2012 Oct 1. PMID 22884528, Free PMC Article
    5. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in morphogenesis of a branching epithelium IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16952-PA
    CG16952-PB
    CG16952-PC
    CG16952-PD
    CG16952-PE
    CG16952-PH

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      15870183..15875607
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298375.1 → NP_001285304.1  uncharacterized protein Dmel_CG16952, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285304.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY90, X2JFM8
      Conserved Domains (4) summary
      smart00225
      Location:169 → 244
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:448 → 524
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:162 → 266
      BTB; BTB/POZ domain
      cl02518
      Location:303 → 321
      BTB; BTB/POZ domain

    2. NM_206740.3 → NP_996463.1  uncharacterized protein Dmel_CG16952, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996463.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY90, Q9VXM6
      Conserved Domains (4) summary
      smart00225
      Location:169 → 244
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:448 → 524
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:162 → 266
      BTB; BTB/POZ domain
      cl02518
      Location:303 → 321
      BTB; BTB/POZ domain

    3. NM_001169293.2 → NP_001162764.1  uncharacterized protein Dmel_CG16952, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162764.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY90, Q9VXM6
      Conserved Domains (4) summary
      smart00225
      Location:169 → 244
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:448 → 524
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:162 → 266
      BTB; BTB/POZ domain
      cl02518
      Location:303 → 321
      BTB; BTB/POZ domain

    4. NM_001369984.1 → NP_001356947.1  uncharacterized protein Dmel_CG16952, isoform H [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K4K0, Q8SY90
      Conserved Domains (3) summary
      cd18283
      Location:166 → 256
      BTB1_POZ_BTBD7; first BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18284
      Location:270 → 427
      BTB2_POZ_BTBD7; second BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB/POZ domain-containing protein 7 (BTBD7)
      cd18489
      Location:432 → 529
      BACK_BTBD7; BACK (BTB and C-terminal Kelch) domain found in BTB/POZ domain-containing protein 7 (BTBD7)

    5. NM_132857.4 → NP_573085.2  uncharacterized protein Dmel_CG16952, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573085.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY90, Q9VXM6
      Related
      FBpp0073924
      Conserved Domains (4) summary
      smart00225
      Location:169 → 244
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:448 → 524
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:162 → 266
      BTB; BTB/POZ domain
      cl02518
      Location:303 → 321
      BTB; BTB/POZ domain

    6. NM_206741.3 → NP_996464.1  uncharacterized protein Dmel_CG16952, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_996464.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SY90, Q9VXM6
      Conserved Domains (4) summary
      smart00225
      Location:169 → 244
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00875
      Location:448 → 524
      BACK; BTB And C-terminal Kelch
      pfam00651
      Location:162 → 266
      BTB; BTB/POZ domain
      cl02518
      Location:303 → 321
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A4D6K4K0 A0A4D6K4K0
    Q8SY90 Q8SY90
    Q9VXM6 Q9VXM6
    X2JFM8 X2JFM8

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