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    CG13999 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33826, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13999provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031753
    Locus tag
    Dmel_CG13999
    See related
    AllianceGenome:FB:FBgn0031753
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13999
    Summary
    Predicted to be involved in cilium assembly. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in Joubert syndrome 16. Orthologous to human TMEM138 (transmembrane protein 138). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13999 in Genome Data Viewer
    Location:
    26A3-26A3; 2-18 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (5955312..5956466, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (5955312..5956466, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Glycerol-3-phosphate dehydrogenase 1 Neighboring gene long non-coding RNA:CR44986 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vitelline membrane 26Ab

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    2. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    3. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    4. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    5. A protein interaction map of Drosophila melanogaster. Giot L, et al. Science, 2003 Dec 5. PMID 14605208

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cilium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13999-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      5955312..5956466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135128.3 → NP_608972.1  uncharacterized protein Dmel_CG13999 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608972.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4T1, Q9VMK8
      Related
      FBpp0078781
      Conserved Domains (1) summary
      pfam14935
      Location:40 → 161
      TMEM138; Transmembrane protein 138
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VMK8 Q9VMK8

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