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    CG16903 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31178, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG16903provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040394
    Locus tag
    Dmel_CG16903
    See related
    AllianceGenome:FB:FBgn0040394
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO03040301.211; Dmel\CG16903; EG:67A9.2
    Summary
    Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in organism. Orthologous to several human genes including CCNL1 (cyclin L1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG16903 in Genome Data Viewer
    Location:
    2C10-2C10; 1-0.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2078343..2080405, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (1972376..1974438, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44382 Neighboring gene RNA 3'-terminal phosphate cyclase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Uncoordinated 76 Neighboring gene corkscrew

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Nutrient-Responsive Molecular Chaperone Hsp90 Supports Growth and Development in Drosophila. Ohhara Y, et al. Front Physiol, 2021. PMID 34239451, Free PMC Article
    2. PRE-mediated bypass of two Su(Hw) insulators targets PcG proteins to a downstream promoter. Comet I, et al. Dev Cell, 2006 Jul. PMID 16824958
    3. A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Baumbach J, et al. Cell Metab, 2014 Feb 4. PMID 24506874
    4. A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila. Port F, et al. Elife, 2020 Feb 13. PMID 32053108, Free PMC Article
    5. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cyclin-dependent protein serine/threonine kinase regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG16903-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2078343..2080405 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130624.3 → NP_569980.1  uncharacterized protein Dmel_CG16903 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569980.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W526
      Related
      FBpp0070418
      Conserved Domains (2) summary
      smart00385
      Location:235 → 321
      CYCLIN; domain present in cyclins, TFIIB and Retinoblastoma
      cd00043
      Location:114 → 203
      CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB and Retinoblastoma (RB).The cyclins consist of 8 classes of cell cycle regulators that regulate cyclin dependent kinases (CDKs). TFIIB ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9U1K6 Q9U1K6
    Q9W526 Q9W526

    Gene LinkOut

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