CG4860 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG4860provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0037999
Locus tag: Dmel_CG4860
See related: AllianceGenome:FB:FBgn0037999
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: ACAD11; ACADS; Dmel\CG4860
Summary: Predicted to enable short-chain fatty acyl-CoA dehydrogenase activity. Predicted to be involved in butyrate catabolic process and fatty acid beta-oxidation using acyl-CoA dehydrogenase. Predicted to be active in mitochondrion. Is expressed in embryonic/larval oenocyte and organism. Human ortholog(s) of this gene implicated in alcohol use disorder and short chain acyl-CoA dehydrogenase deficiency. Orthologous to human ACADS (acyl-CoA dehydrogenase short chain). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (12219881..12221464, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (8045603..8047186, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables acyl-CoA dehydrogenase activity	IEA Inferred from Electronic Annotation more info
enables acyl-CoA dehydrogenase activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables short-chain fatty acyl-CoA dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in butyrate catabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in fatty acid beta-oxidation	ISS Inferred from Sequence or Structural Similarity more info	PubMed
involved_in fatty acid beta-oxidation using acyl-CoA dehydrogenase	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

NP_650163.2

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The following sections contain reference sequences that belong to a specific genome build. Explain