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    Cul6 Cullin 6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39474, updated on 9-Dec-2024

    Summary

    Official Symbol
    Cul6provided by FlyBase
    Official Full Name
    Cullin 6provided by FlyBase
    Primary source
    FLYBASE:FBgn0036332
    Locus tag
    Dmel_CG11261
    See related
    AllianceGenome:FB:FBgn0036332
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG11261; CUL6; Cullin6; Dmel\CG11261
    Summary
    Predicted to enable protein-macromolecule adaptor activity and ubiquitin protein ligase binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process and protein ubiquitination. Predicted to be part of SCF ubiquitin ligase complex. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Cul6 in Genome Data Viewer
    Location:
    69F5-69F5; 3-39 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13009399..13011685, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13002499..13004785, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene MICAL-like Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SCF ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    cullin 6
    Names
    CG11261-PA
    Cul6-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13009399..13011685 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140363.3NP_648620.1  cullin 6 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648620.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU33
      Related
      FBpp0075633
      Conserved Domains (3) summary
      smart00182
      Location:362500
      CULLIN; Cullin
      COG5647
      Location:25670
      COG5647; Cullin, a subunit of E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]
      pfam10557
      Location:606661
      Cullin_Nedd8; Cullin protein neddylation domain