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    Tes Testin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tesprovided by FlyBase
    Official Full Name
    Testinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034223
    Locus tag
    Dmel_CG6522
    See related
    AllianceGenome:FB:FBgn0034223
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6522; Dmel\CG6522; dTES
    Summary
    Predicted to enable zinc ion binding activity. Located in actin cytoskeleton and cytoplasm. Is expressed in larval central nervous system. Orthologous to human LMCD1 (LIM and cysteine rich domains 1) and TES (testin LIM domain protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tes in Genome Data Viewer
    Location:
    54B16-54B16; 2-82 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17465879..17469177, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13353384..13356682, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene roadblock Neighboring gene uncharacterized protein Neighboring gene quaking related 54B Neighboring gene insensible

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Generation of stable Drosophila cell lines using multicistronic vectors. González M, et al. Sci Rep, 2011. PMID 22355594, Free PMC Article
    2. Slam protein dictates subcellular localization and translation of its own mRNA. Yan S, et al. PLoS Biol, 2017 Dec. PMID 29206227, Free PMC Article
    3. Insensible is a novel nuclear inhibitor of Notch activity in Drosophila. Coumailleau F, et al. PLoS One, 2014. PMID 24902027, Free PMC Article
    4. Retracing the path of planar cell polarity. Schenkelaars Q, et al. BMC Evol Biol, 2016 Apr 2. PMID 27039172, Free PMC Article
    5. Molecular organization of Drosophila neuroendocrine cells by Dimmed. Park D, et al. Curr Biol, 2011 Sep 27. PMID 21885285, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    testin
    Names
    CG6522-PA
    Tes-PA
    testin ortholog

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17465879..17469177 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137371.4 → NP_611215.1  testin [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611215.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZAT5, H1UUM7
      Related
      FBpp0086110
      Conserved Domains (4) summary
      cd09340
      Location:627 → 684
      LIM1_Testin_like; The first LIM domain of Testin-like family
      cd09341
      Location:691 → 748
      LIM2_Testin_like; The second LIM domain of Testin-like family
      cd09829
      Location:110 → 197
      PET_testin; The PET domain of Testin
      cl02475
      Location:755 → 810
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZAT5 A1ZAT5
    Q8T0B0 Q8T0B0

    Gene LinkOut

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