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    CG15306 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31961, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15306provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030191
    Locus tag
    Dmel_CG15306
    See related
    AllianceGenome:FB:FBgn0030191
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15306
    Summary
    Predicted to enable microtubule plus-end binding activity. Predicted to be involved in protein localization to microtubule; regulation of microtubule polymerization or depolymerization; and spindle assembly. Predicted to be active in microtubule cytoskeleton. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15306 in Genome Data Viewer
    Location:
    9B7-9B7; 1-31 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10330160..10331818, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10224193..10225851, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene alpha-Mannosidase class I a Neighboring gene uncharacterized protein Neighboring gene GIP-like Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Drosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle. Rogers SL, et al. J Cell Biol, 2002 Sep 2. PMID 12213835, Free PMC Article
    2. Identification of JAK/STAT signalling components by genome-wide RNA interference. Müller P, et al. Nature, 2005 Aug 11. PMID 16094372
    3. Expression profiling of a hypercontraction-induced myopathy in Drosophila suggests a compensatory cytoskeletal remodeling response. Montana ES, et al. J Biol Chem, 2006 Mar 24. PMID 16415344
    4. Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells. Robinson BV, et al. Biochem Soc Trans, 2020 Oct 30. PMID 32897294, Free PMC Article
    5. Genome-Wide Mapping Targets of the Metazoan Chromatin Remodeling Factor NURF Reveals Nucleosome Remodeling at Enhancers, Core Promoters and Gene Insulators. Kwon SY, et al. PLoS Genet, 2016 Apr. PMID 27046080, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule plus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization to microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of microtubule polymerization or depolymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasmic microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule organizing center IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in microtubule plus-end IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in spindle midzone IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15306-PA
    CG15306-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10330160..10331818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132390.2 → NP_572618.1  uncharacterized protein Dmel_CG15306, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572618.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2W2
      Related
      FBpp0071405
      Conserved Domains (1) summary
      pfam00307
      Location:20 → 103
      CH; Calponin homology (CH) domain

    2. NM_001272474.1 → NP_001259403.1  uncharacterized protein Dmel_CG15306, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259403.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W2W2
      Conserved Domains (1) summary
      pfam00307
      Location:20 → 103
      CH; Calponin homology (CH) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T3Q9 Q8T3Q9
    Q9W2W2 Q9W2W2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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