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    CG7564 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39956, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7564provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036734
    Locus tag
    Dmel_CG7564
    See related
    AllianceGenome:FB:FBgn0036734
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Alsin2; Dmel\CG7564
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site recognition. Part of precatalytic spliceosome. Is expressed in adult head. Orthologous to several human genes including LUC7L (LUC7 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7564 in Genome Data Viewer
    Location:
    74D2-74D2; 3-45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17514298..17524740)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17507398..17517840)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Organic anion transporting polypeptide 74D Neighboring gene elevated during infection Neighboring gene U4-U6 small nuclear riboprotein factor 60K Neighboring gene ncRNA Neighboring gene long non-coding RNA:CR45165 Neighboring gene Enhancer of decapping 3 Neighboring gene Nedd4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DX16 is a novel SR protein phosphorylated by DOA. Wan Y, et al. Mol Cell Biochem, 2008 Jan. PMID 17828581
    2. Proper splicing contributes to visual function in the aging Drosophila eye. Stegeman R, et al. Aging Cell, 2018 Oct. PMID 30003673, Free PMC Article
    3. Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity. Ma S, et al. Aging Cell, 2018 Aug. PMID 29671950, Free PMC Article
    4. A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis. Deivasigamani S, et al. Biol Open, 2014 Oct 31. PMID 25361581, Free PMC Article
    5. Quantitative Proteomic and Metabolomic Profiling Reveals Altered Mitochondrial Metabolism and Folate Biosynthesis Pathways in the Aging Drosophila Eye. Hall H, et al. Mol Cell Proteomics, 2021. PMID 34332122, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splice site recognition IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splice site recognition IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U1 snRNP IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of U1 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7564-PA
    CG7564-PB
    CG7564-PC
    CG7564-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17514298..17524740
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300169.1 → NP_001287098.1  uncharacterized protein Dmel_CG7564, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VVI1
      Conserved Domains (2) summary
      COG5200
      Location:11 → 248
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:12 → 246
      LUC7; LUC7 N_terminus

    2. NM_001300168.1 → NP_001287097.1  uncharacterized protein Dmel_CG7564, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287097.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VVI1
      Conserved Domains (2) summary
      COG5200
      Location:11 → 248
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:12 → 246
      LUC7; LUC7 N_terminus

    3. NM_001275060.1 → NP_001261989.1  uncharacterized protein Dmel_CG7564, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261989.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VVI1
      Conserved Domains (2) summary
      COG5200
      Location:11 → 248
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:12 → 246
      LUC7; LUC7 N_terminus

    4. NM_140734.3 → NP_648991.1  uncharacterized protein Dmel_CG7564, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648991.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VVI1
      Related
      FBpp0074941
      Conserved Domains (2) summary
      COG5200
      Location:11 → 248
      LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
      pfam03194
      Location:12 → 246
      LUC7; LUC7 N_terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVI1 Q9VVI1

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