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    HXT10 hexose transporter HXT10 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850536, updated on 9-Dec-2024

    Summary

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    Official Symbol
    HXT10
    Official Full Name
    hexose transporter HXT10
    Primary source
    SGD:S000001883
    Locus tag
    YFL011W
    See related
    AllianceGenome:SGD:S000001883; FungiDB:YFL011W; VEuPathDB:YFL011W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables hexose transmembrane transporter activity. Involved in hexose transmembrane transport. Located in cell periphery; fungal-type vacuole; and mitochondrion. Orthologous to human SLC2A6 (solute carrier family 2 member 6) and SLC2A8 (solute carrier family 2 member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See HXT10 in Genome Data Viewer
    Location:
    chromosome: VI
    Exon count:
    1
    Sequence:
    Chromosome: VI; NC_001138.5 (112345..113985)

    Chromosome VI - NC_001138.5Genomic Context describing neighboring genes Neighboring gene Ies1p Neighboring gene uncharacterized protein Neighboring gene Aua1p Neighboring gene Wwm1p Neighboring gene SCF ubiquitin ligase complex subunit CDC4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001138.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters. Subtil T, et al. Biotechnol Biofuels, 2011 Oct 12. PMID 21992610, Free PMC Article
    2. Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid. Liu Z, et al. Biochem Biophys Res Commun, 2006 Dec 15. PMID 17064664, Free PMC Article
    3. Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase. Scarcelli JJ, et al. FEMS Yeast Res, 2012 May. PMID 22151002, Free PMC Article
    4. Sequestration of mRNAs Modulates the Timing of Translation during Meiosis in Budding Yeast. Jin L, et al. Mol Cell Biol, 2015 Oct. PMID 26217015, Free PMC Article
    5. Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. Wieczorke R, et al. FEBS Lett, 1999 Dec 31. PMID 10618490

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-glucose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables carbohydrate:proton symporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fructose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables galactose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables mannose transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in carbohydrate transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in fructose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in galactose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in hexose transmembrane transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mannose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    hexose transporter HXT10
    NP_116644.1
    • Hexose transporter; expressed at low levels and expression is repressed by glucose

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001138.5 Reference assembly

      Range
      112345..113985
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179955.1 → NP_116644.1  TPA: hexose transporter HXT10 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_116644.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VTL8, P43581
      UniProtKB/TrEMBL
      B3LUJ8, B5VI16, C7GY98, C8Z7S5
      Conserved Domains (1) summary
      pfam00083
      Location:52 → 512
      Sugar_tr; Sugar (and other) transporter
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P43581.1

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