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    E(var)3-9 Enhancer of variegation 3-9 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 41073, updated on 9-Dec-2024

    Summary

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    Official Symbol
    E(var)3-9provided by FlyBase
    Official Full Name
    Enhancer of variegation 3-9provided by FlyBase
    Primary source
    FLYBASE:FBgn0260243
    Locus tag
    Dmel_CG11971
    See related
    AllianceGenome:FB:FBgn0260243
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    1E9; anon-EST:fe1E9; anon1E9; Anon1E9; CG11971; Dmel\CG11971; E-var(3)9
    Summary
    Predicted to enable zinc ion binding activity. Involved in chromatin organization. Predicted to be active in nucleus. Is expressed in organism. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See E(var)3-9 in Genome Data Viewer
    Location:
    85C1-85C1; 3-48 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (8990645..8992949, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (4816367..4818671, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene ichor Neighboring gene Carbonic anhydrase beta Neighboring gene Ras-related GTP binding A/B Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Effects of Chromatin Structure Modifiers on the trans-Acting Heterochromatin Position Effect in Drosophila melanogaster. Solodovnikov AA, et al. Dokl Biochem Biophys, 2023 Dec. PMID 38379078
    2. Large number of replacement polymorphisms in rapidly evolving genes of Drosophila. Implications for genome-wide surveys of DNA polymorphism. Schmid KJ, et al. Genetics, 1999 Dec. PMID 10581279, Free PMC Article
    3. Identification and characterization of proteins involved in nuclear organization using Drosophila GFP protein trap lines. Rohrbaugh M, et al. PLoS One, 2013. PMID 23341925, Free PMC Article
    4. Germline protein, Cup, non-cell autonomously limits migratory cell fate in Drosophila oogenesis. Saha B, et al. PLoS Genet, 2023 Feb. PMID 36791149, Free PMC Article
    5. Sox21b underlies the rapid diversification of a novel male genital structure between Drosophila species. Ridgway AM, et al. Curr Biol, 2024 Mar 11. PMID 38309269

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    enhancer of variegation 3-9
    Names
    CG11971-PA
    E(var)3-9-PA
    anon-fast-evolving-1E9

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      8990645..8992949 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141595.3 → NP_649852.2  enhancer of variegation 3-9 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649852.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16044, Q9TVG9, Q9VHJ3
      Related
      FBpp0081490
      Conserved Domains (4) summary
      PHA00732
      Location:310 → 358
      PHA00732; hypothetical protein
      sd00017
      Location:281 → 303
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam07776
      Location:18 → 102
      zf-AD; Zinc-finger associated domain (zf-AD)
      pfam12756
      Location:253 → 334
      zf-C2H2_2; C2H2 type zinc-finger (2 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O16044 O16044
    Q7KLT3 Q7KLT3
    Q8SZ92 Q8SZ92
    Q9U4P6 Q9U4P6
    Q9U4P7 Q9U4P7
    Q9U4P8 Q9U4P8
    Q9U4P9 Q9U4P9
    Q9VHJ3 Q9VHJ3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
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