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    CG2685 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31259, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2685provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0024998
    Locus tag
    Dmel_CG2685
    See related
    AllianceGenome:FB:FBgn0024998
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG2685; EG:100G10.1
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to human WBP11 (WW domain binding protein 11). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2685 in Genome Data Viewer
    Location:
    3B3-3B3; 1-1.5 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (2711756..2713960, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (2605789..2607993, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2B subunit beta Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene female sterile (1) Yb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
    2. Definition of global and transcript-specific mRNA export pathways in metazoans. Farny NG, et al. Genes Dev, 2008 Jan 1. PMID 18086857, Free PMC Article
    3. Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis. Zhou J, et al. Sci Adv, 2019 Sep. PMID 31555733, Free PMC Article
    4. Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. Herold N, et al. Mol Cell Biol, 2009 Jan. PMID 18981222, Free PMC Article
    5. spenito is required for sex determination in Drosophila melanogaster. Yan D, et al. Proc Natl Acad Sci U S A, 2015 Sep 15. PMID 26324914, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome HDA PubMed 
    part_of precatalytic spliceosome HDA PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2685-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      2711756..2713960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_130667.4 → NP_570023.1  uncharacterized protein Dmel_CG2685 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_570023.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O76861
      Related
      FBpp0070476
      Conserved Domains (1) summary
      pfam09429
      Location:12 → 92
      Wbp11; WW domain binding protein 11
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O76861 O76861
    Q8MYX2 Q8MYX2

    Gene LinkOut

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