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    Ir7a Ionotropic receptor 7a [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31686, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir7aprovided by FlyBase
    Official Full Name
    Ionotropic receptor 7aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029961
    Locus tag
    Dmel_CG12663
    See related
    AllianceGenome:FB:FBgn0029961
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    7a; CG12663; DmelIR7a; Dmel\CG12663; IR7a
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in membrane. Is expressed in several structures, including adult pharynx; gustatory receptor neurons; labellum; larval gnathal ganglion; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir7a in Genome Data Viewer
    Location:
    7B8-7B8; 1-20 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (7764982..7766826)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (7659015..7660859)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Rab39 Neighboring gene Translocase of outer membrane 40 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Taste coding of heavy metal ion-induced avoidance in Drosophila. Li X, et al. iScience, 2023 May 19. PMID 37128604, Free PMC Article
    2. Soft Selective Sweep on Chemosensory Genes Correlates with Ancestral Preference for Toxic Noni in a Specialist Drosophila Population. Ferreira EA, et al. Genes (Basel), 2020 Dec 29. PMID 33383708, Free PMC Article
    3. The histone H3.3 chaperone HIRA is essential for chromatin assembly in the male pronucleus. Loppin B, et al. Nature, 2005 Oct 27. PMID 16251970
    4. A molecular and neuronal basis for amino acid sensing in the Drosophila larva. Croset V, et al. Sci Rep, 2016 Dec 16. PMID 27982028, Free PMC Article
    5. Acid and Alkali Taste Sensation. Pandey P, et al. Metabolites, 2023 Nov 4. PMID 37999227, Free PMC Article

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of bitter taste IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sensory perception of taste IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 7a
    Names
    CG12663-PA
    Ir7a-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      7764982..7766826
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132178.1 → NP_572406.1  ionotropic receptor 7a [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572406.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9W3P8
      Related
      FBpp0071032, FBtr0071075
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W3P8 Q9W3P8

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