CG15743 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG15743provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0030465
Locus tag: Dmel_CG15743
See related: AllianceGenome:FB:FBgn0030465
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: Dmel\CG15743
Summary: Predicted to enable 3'-nucleotidase activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Located in endomembrane system. Is expressed in adult head; embryonic/larval salivary gland; embryonic/larval salivary gland body; organism; and salivary gland body primordium. Human ortholog(s) of this gene implicated in chondrodysplasia with joint dislocations gPAPP type. Orthologous to human BPNT2 (3'(2'), 5'-bisphosphate nucleotidase 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 11E9-11E9; 1-42 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (13285707..13287741)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (13179740..13181774)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables 3'-nucleotidase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in phosphatidylinositol phosphate biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endomembrane system	HDA more info	PubMed
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG15743-PA; CG15743-PB; CG15743-PC

NP_001259511.1

EC 3.1.3.6

NP_001285197.1

EC 3.1.3.6

NP_572869.1

EC 3.1.3.6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

13285707..13287741

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001298268.1 → NP_001285197.1 uncharacterized protein Dmel_CG15743, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285197.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9VYF2

UniProtKB/TrEMBL

M9PH13

Conserved Domains (1) summary

cd01640
Location:59 → 342

IPPase; IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may ...
NM_132641.2 → NP_572869.1 uncharacterized protein Dmel_CG15743, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_572869.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9VYF2

UniProtKB/TrEMBL

M9PH13

Related

FBpp0073586

Conserved Domains (1) summary

cd01640
Location:59 → 342

IPPase; IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may ...
NM_001272582.1 → NP_001259511.1 uncharacterized protein Dmel_CG15743, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001259511.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q9VYF2

UniProtKB/TrEMBL

M9PH13

Conserved Domains (1) summary

cd01640
Location:59 → 342

IPPase; IPPase; Inositol polyphosphate-1-phosphatase, a member of the Mg++ dependent family of inositol monophosphatase-like domains, hydrolyzes the 1' position phosphate from inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate. Members in this group may ...