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    CG8245 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35503, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8245provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033031
    Locus tag
    Dmel_CG8245
    See related
    AllianceGenome:FB:FBgn0033031
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8245
    Summary
    Is expressed in adult head; embryonic brain; larval nervous system; and larval ventral nerve cord. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Orthologous to human TMEM53 (transmembrane protein 53). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8245 in Genome Data Viewer
    Location:
    41F6-41F6; 2-55 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (5668383..5669986)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (1555888..1557491)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene CCR4-NOT transcription complex subunit 3 Neighboring gene long non-coding RNA:CR45472 Neighboring gene kune-kune Neighboring gene scarface

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: a window on the heterochromatin-euchromatin junction. Myster SH, et al. Genetics, 2004 Feb. PMID 15020470, Free PMC Article
    2. FISH analysis of Drosophila melanogaster heterochromatin using BACs and P elements. Corradini N, et al. Chromosoma, 2003 Jul. PMID 12827380
    3. Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila. Caizzi R, et al. PLoS Genet, 2016 Aug. PMID 27513559, Free PMC Article
    4. Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. Haussmann IU, et al. Genome Biol, 2008 Apr 17. PMID 18419806, Free PMC Article
    5. Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders. Sechi S, et al. Cells, 2021 Sep 6. PMID 34571985, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8245-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      5668383..5669986
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136334.3 → NP_610178.2  uncharacterized protein Dmel_CG8245 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610178.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z6G9, Q8SXH2
      Related
      FBpp0085372
      Conserved Domains (1) summary
      pfam05705
      Location:76 → 314
      DUF829; Eukaryotic protein of unknown function (DUF829)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z6G9 A1Z6G9
    Q8SXH2 Q8SXH2

    Gene LinkOut

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