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    Ir48b Ionotropic receptor 48b [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36254, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir48bprovided by FlyBase
    Official Full Name
    Ionotropic receptor 48bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033648
    Locus tag
    Dmel_CG13195
    See related
    AllianceGenome:FB:FBgn0033648
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    48b; CG13195; DmelIR48b; Dmel\CG13195; IR48b
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in larval gustatory receptor neuron of the dorsal pharyngeal sense organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir48b in Genome Data Viewer
    Location:
    48C2-48C2; 2-65 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (11700647..11702449, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (7588152..7589954, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 48a Neighboring gene long non-coding RNA:CR45377 Neighboring gene pyramus

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extensive local adaptation within the chemosensory system following Drosophila melanogaster's global expansion. Arguello JR, et al. Nat Commun, 2016 Jun 13. PMID 27292132, Free PMC Article
    2. FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation. Kadam S, et al. Development, 2009 Mar. PMID 19158183, Free PMC Article
    3. Candidate ionotropic taste receptors in the Drosophila larva. Stewart S, et al. Proc Natl Acad Sci U S A, 2015 Apr 7. PMID 25825777, Free PMC Article
    4. The Drosophila IR20a clade of ionotropic receptors are candidate taste and pheromone receptors. Koh TW, et al. Neuron, 2014 Aug 20. PMID 25123314, Free PMC Article
    5. A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster. Sang J, et al. Elife, 2024 Apr 4. PMID 38573740, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 48b
    Names
    CG13195-PA
    Ir48b-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      11700647..11702449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136853.1 → NP_610697.1  ionotropic receptor 48b [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610697.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8N9
      Related
      FBpp0087185, FBtr0088080
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z8N9 A1Z8N9

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