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    Ir56d Ionotropic receptor 56d [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37252, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir56dprovided by FlyBase
    Official Full Name
    Ionotropic receptor 56dprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034458
    Locus tag
    Dmel_CG15904
    See related
    AllianceGenome:FB:FBgn0034458
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    56d; CG15904; DmelIR56d; Dmel\CG15904; IR56d
    Summary
    Enables ionotropic taste receptor activity. Involved in detection of chemical stimulus involved in sensory perception of taste and proboscis extension reflex. Predicted to be located in membrane. Is expressed in adult labellum sensillum; bristle sensory neurons; carbon dioxide sensitive neurons; metathoracic tarsal bristle; and organism subdivision. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir56d in Genome Data Viewer
    Location:
    56D15-56D15; 2-89 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19511673..19513571, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15399178..15401076, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Ionotropic receptor 56b Neighboring gene Ionotropic receptor 56c Neighboring gene smooth Neighboring gene transfer RNA:Glutamic acid-TTC 1-3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Dietary fatty acids promote sleep through a taste-independent mechanism. Pamboro ELS, et al. Genes Brain Behav, 2020 Apr. PMID 31845509
    2. A subset of sweet-sensing neurons identified by IR56d are necessary and sufficient for fatty acid taste. Tauber JM, et al. PLoS Genet, 2017 Nov. PMID 29121639, Free PMC Article
    3. Ir56d-dependent fatty acid responses in Drosophila uncover taste discrimination between different classes of fatty acids. Brown EB, et al. Elife, 2021 May 5. PMID 33949306, Free PMC Article
    4. Evolution of fatty acid taste in drosophilids. Dey M, et al. Cell Rep, 2023 Oct 31. PMID 37864792, Free PMC Article
    5. Molecular basis of fatty acid taste in Drosophila. Ahn JE, et al. Elife, 2017 Dec 12. PMID 29231818, Free PMC Article

    See all (43) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ionotropic taste receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in detection of chemical stimulus involved in sensory perception of taste IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in proboscis extension reflex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 56d
    Names
    CG15904-PA
    Ir56d-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19511673..19513571 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137588.1 → NP_611432.1  ionotropic receptor 56d [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611432.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBM9
      Related
      FBpp0085686, FBtr0086497
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1ZBM9 A1ZBM9

    Gene LinkOut

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