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    Snmp2 Sensory neuron membrane protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38868, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Snmp2provided by FlyBase
    Official Full Name
    Sensory neuron membrane protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0035815
    Locus tag
    Dmel_CG7422
    See related
    AllianceGenome:FB:FBgn0035815
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    148358_at; CG16832; CG7422; Dmel\CG7422; snmp; SNMP2
    Summary
    Predicted to enable scavenger receptor activity. Predicted to be involved in cellular response to pheromone. Predicted to be active in membrane. Is expressed in embryonic/larval anterior spiracle and testis. Human ortholog(s) of this gene implicated in several diseases, including blood platelet disease (multiple); hemolytic-uremic syndrome; osteoarthritis; pulmonary tuberculosis; and type 2 diabetes mellitus. Orthologous to human CD36 (CD36 molecule (CD36 blood group)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Snmp2 in Genome Data Viewer
    Location:
    66A11-66A11; 3-21 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7733250..7743041, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7726350..7736141, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Medium-chain acyl-CoA dehydrogenase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Volatile pheromone signalling in Drosophila. Smith DP. Physiol Entomol, 2012 Mar 1. PMID 24347807, Free PMC Article
    2. The insect SNMP gene family. Vogt RG, et al. Insect Biochem Mol Biol, 2009 Jul. PMID 19364529
    3. Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. Herboso L, et al. Int J Dev Biol, 2011. PMID 21948708
    4. Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing. Jansen IE, et al. Genome Biol, 2017 Jan 30. PMID 28137300, Free PMC Article
    5. Systematic analysis of olfactory protein-protein interactions network of fruitfly, Drosophila melanogaster. Yang S, et al. Arch Insect Biochem Physiol, 2022 Jun. PMID 35249240

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables scavenger receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to pheromone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    sensory neuron membrane protein 2
    Names
    CG7422-PB
    CG7422-PC
    CG7422-PD
    Snmp2-PB
    Snmp2-PC
    Snmp2-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7733250..7743041 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274610.1 → NP_001261539.1  sensory neuron membrane protein 2, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261539.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0AVW0, A1A6X6, A1A6X7, A1A6Z5, A1A6Z6, A2RVH7, A8W3N7, C9QPB5, E1JI63, Q0E8H2
      UniProtKB/TrEMBL
      H1UUH0
      Conserved Domains (1) summary
      pfam01130
      Location:10 → 543
      CD36; CD36 family

    2. NM_001043128.2 → NP_001036593.1  sensory neuron membrane protein 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036593.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H0RNK6
      Conserved Domains (1) summary
      pfam01130
      Location:10 → 497
      CD36; CD36 family

    3. NM_001169901.1 → NP_001163372.1  sensory neuron membrane protein 2, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163372.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0AVW0, A1A6X6, A1A6X7, A1A6Z5, A1A6Z6, A2RVH7, A8W3N7, C9QPB5, E1JI63, Q0E8H2
      UniProtKB/TrEMBL
      H1UUH0
      Conserved Domains (1) summary
      pfam01130
      Location:10 → 543
      CD36; CD36 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JI63.1 E1JI63
    H1UUH0 H1UUH0

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