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    CG42588 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39457, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42588provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0260965
    Locus tag
    Dmel_CG42588
    See related
    AllianceGenome:FB:FBgn0260965
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD20456; BP1016; CG11008; CG32108; CG34017; Dmel\CG42588
    Old locus tag
    Dmel_CG11008; Dmel_CG32108; Dmel_CG34017
    Summary
    Predicted to be involved in transcription by RNA polymerase III. Predicted to be part of transcription factor TFIIIC complex. Is expressed in spermatozoon. Orthologous to human GTF3C2 (general transcription factor IIIC subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42588 in Genome Data Viewer
    Location:
    69E4-69E5; 3-39 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (12814254..12824650)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (12807354..12817750)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Sin3A-associated protein 130 Neighboring gene uncharacterized protein Neighboring gene Splicing factor 3a subunit 2 Neighboring gene nebulosa Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stable intronic sequence RNAs have possible regulatory roles in Drosophila melanogaster. Pek JW, et al. J Cell Biol, 2015 Oct 26. PMID 26504165, Free PMC Article
    2. Genomic signatures of experimental adaptive radiation in Drosophila. Michalak P, et al. Mol Ecol, 2019 Feb. PMID 30375065
    3. A misexpression screen to identify regulators of Drosophila larval hemocyte development. Stofanko M, et al. Genetics, 2008 Sep. PMID 18757933, Free PMC Article
    4. A computational and experimental approach to validating annotations and gene predictions in the Drosophila melanogaster genome. Yandell M, et al. Proc Natl Acad Sci U S A, 2005 Feb 1. PMID 15668397, Free PMC Article
    5. Identification of genes that promote or inhibit olfactory memory formation in Drosophila. Walkinshaw E, et al. Genetics, 2015 Apr. PMID 25644700, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42588-PA
    CG42588-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      12814254..12824650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140347.4 → NP_648604.2  uncharacterized protein Dmel_CG42588, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648604.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VU16
      Conserved Domains (2) summary
      PHA03247
      Location:11 → 541
      PHA03247; large tegument protein UL36; Provisional
      sd00039
      Location:2363 → 2403
      7WD40; WD40 repeat [structural motif]

    2. NM_001202159.2 → NP_001189088.1  uncharacterized protein Dmel_CG42588, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001189088.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9MSL0
      Conserved Domains (2) summary
      pfam05793
      Location:825 → 1083
      TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
      sd00039
      Location:2338 → 2378
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9MSL0 M9MSL0
    Q8MRV4 Q8MRV4
    Q9VU16 Q9VU16

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