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    Sgf11 SAGA associated factor 11kDa [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40035, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Sgf11provided by FlyBase
    Official Full Name
    SAGA associated factor 11kDaprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036804
    Locus tag
    Dmel_CG13379
    See related
    AllianceGenome:FB:FBgn0036804
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13379; Dmel\CG13379; dSgf11; sgf11
    Summary
    Involved in chromatin organization and positive regulation of DNA-templated transcription. Located in nucleus. Part of DUBm complex and SAGA complex. Orthologous to human ATXN7L3 (ataxin 7 like 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Sgf11 in Genome Data Viewer
    Location:
    75D6-75D6; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18681037..18681836, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18674137..18674936, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Charged multivesicular body protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Progressive degeneration in a new Drosophila model of spinocerebellar ataxia type 7. Sujkowski A, et al. Sci Rep, 2024 Jun 21. PMID 38906973, Free PMC Article
    2. CTCF and Sgfl1 proteins form alternative complexes with ENY2 proteins. Bonchuk AN, et al. Dokl Biochem Biophys, 2016 May. PMID 27417714
    3. Enzymatic modules of the SAGA chromatin-modifying complex play distinct roles in Drosophila gene expression and development. Li X, et al. Genes Dev, 2017 Aug 1. PMID 28887412, Free PMC Article
    4. Nipped-A regulates the Drosophila circadian clock via histone deubiquitination. Bu B, et al. EMBO J, 2020 Jan 2. PMID 31538360, Free PMC Article
    5. Transcriptome Profiling Identifies Multiplexin as a Target of SAGA Deubiquitinase Activity in Glia Required for Precise Axon Guidance During Drosophila Visual Development. Ma J, et al. G3 (Bethesda), 2016 Aug 9. PMID 27261002, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of DNA-templated transcription IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of DUBm complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SAGA complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SAGA associated factor 11kDa
    Names
    CG13379-PB
    Sgf11-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18681037..18681836 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001104168.2 → NP_001097638.1  SAGA associated factor 11kDa [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097638.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q4V5G1, Q4V623, Q9VVR6
      Conserved Domains (1) summary
      pfam08209
      Location:102 → 134
      Sgf11; Sgf11 (transcriptional regulation protein)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVR6.2 Q9VVR6

    Gene LinkOut

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