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    CG7694 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42230, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7694provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0038627
    Locus tag
    Dmel_CG7694
    See related
    AllianceGenome:FB:FBgn0038627
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:LP11469; Dmel\CG7694
    Summary
    Predicted to enable ubiquitin protein ligase activity and zinc ion binding activity. Predicted to be involved in protein autoubiquitination. Predicted to be active in cytoplasm. Orthologous to human RNF181 (ring finger protein 181). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7694 in Genome Data Viewer
    Location:
    91B4-91B5; 3-64 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18573091..18590726)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14398813..14416448)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene hemotin Neighboring gene frayed Neighboring gene uncharacterized protein Neighboring gene qin Neighboring gene Testis-specific serine/threonine kinase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unlimited Genetic Switches for Cell-Type-Specific Manipulation. Garcia-Marques J, et al. Neuron, 2019 Oct 23. PMID 31395429
    2. A Genome-Wide Screen for Dendritically Localized RNAs Identifies Genes Required for Dendrite Morphogenesis. Misra M, et al. G3 (Bethesda), 2016 Aug 9. PMID 27260999, Free PMC Article
    3. A screen for E3 ubiquitination ligases that genetically interact with the adaptor protein Cindr during Drosophila eye patterning. Ketosugbo KF, et al. PLoS One, 2017. PMID 29117266, Free PMC Article
    4. Comprehensively surveying structure and function of RING domains from Drosophila melanogaster. Ying M, et al. PLoS One, 2011. PMID 21912646, Free PMC Article
    5. Generation of LexA enhancer-trap lines in Drosophila by an international scholastic network. Kim ES, et al. G3 (Bethesda), 2023 Aug 30. PMID 37279923, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein autoubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7694-PA
    CG7694-PB
    CG7694-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      18573091..18590726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_142472.4 → NP_650729.1  uncharacterized protein Dmel_CG7694, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_650729.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B7Z0M4, Q8IGZ5, Q9VE61
      UniProtKB/TrEMBL
      A0A0B4LHA6
      Related
      FBpp0083052
      Conserved Domains (1) summary
      pfam13639
      Location:69 → 111
      zf-RING_2; Ring finger domain

    2. NM_001300465.1 → NP_001287394.1  uncharacterized protein Dmel_CG7694, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287394.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B7Z0M4, Q8IGZ5, Q9VE61
      UniProtKB/TrEMBL
      A0A0B4LHA6
      Conserved Domains (1) summary
      pfam13639
      Location:69 → 111
      zf-RING_2; Ring finger domain

    3. NM_001144604.1 → NP_001138076.1  uncharacterized protein Dmel_CG7694, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138076.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      B7Z0M4, Q8IGZ5, Q9VE61
      UniProtKB/TrEMBL
      A0A0B4LHA6
      Conserved Domains (1) summary
      pfam13639
      Location:69 → 111
      zf-RING_2; Ring finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LHA6 A0A0B4LHA6
    Q9VE61.1 Q9VE61

    Gene LinkOut

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