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    CG4960 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43115, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4960provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039371
    Locus tag
    Dmel_CG4960
    See related
    AllianceGenome:FB:FBgn0039371
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:AT31258; Dmel\CG4960
    Summary
    Predicted to be involved in regulation of intracellular transport. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Orthologous to human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4960 in Genome Data Viewer
    Location:
    96F3-96F3; 3-89 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25786329..25787298, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21612051..21613020, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolution of three parent genes and their retrogene copies in Drosophila species. O'Neill RS, et al. Int J Evol Biol, 2013. PMID 23841016, Free PMC Article
    2. Modeling of axonal endoplasmic reticulum network by spastic paraplegia proteins. Yalçın B, et al. Elife, 2017 Jul 25. PMID 28742022, Free PMC Article
    3. Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair. Nakamura M, et al. PLoS Genet, 2020 Dec. PMID 33306674, Free PMC Article
    4. Retroposed new genes out of the X in Drosophila. Betrán E, et al. Genome Res, 2002 Dec. PMID 12466289, Free PMC Article
    5. Burst of young retrogenes and independent retrogene formation in mammals. Pan D, et al. PLoS One, 2009. PMID 19325906, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of intracellular transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4960-PA
    CG4960-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25786329..25787298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300604.1 → NP_001287533.1  uncharacterized protein Dmel_CG4960, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287533.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8S3, Q9VBM3
      Conserved Domains (1) summary
      pfam03134
      Location:66 → 154
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    2. NM_143172.2 → NP_651429.1  uncharacterized protein Dmel_CG4960, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651429.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8T8S3, Q9VBM3
      Related
      FBpp0084293
      Conserved Domains (1) summary
      pfam03134
      Location:66 → 154
      TB2_DP1_HVA22; TB2/DP1, HVA22 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8T8S3 Q8T8S3
    Q9VBM3 Q9VBM3

    Gene LinkOut

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