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    Osi23 Osiris 23 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43615, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Osi23provided by FlyBase
    Official Full Name
    Osiris 23provided by FlyBase
    Primary source
    FLYBASE:FBgn0039771
    Locus tag
    Dmel_CG15538
    See related
    AllianceGenome:FB:FBgn0039771
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15538; Dmel\CG15538; gox; Gox
    Summary
    Involved in cuticle development. Located in endosome membrane. Is expressed in peripodial epithelium of eye disc. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Osi23 in Genome Data Viewer
    Location:
    99F4-99F4; 3-100 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (30444076..30445046, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (26269798..26270768, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene aralar1 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Form and function of the apical extracellular matrix: new insights from Caenorhabditis elegans, Drosophila melanogaster, and the vertebrate inner ear. Li Zheng S, et al. Fac Rev, 2020. PMID 33659959, Free PMC Article
    2. Tracheal expression of Osiris gene family in Drosophila. Scholl A, et al. Gene Expr Patterns, 2018 Jun. PMID 29548969
    3. Osiris gene family defines the cuticle nanopatterns of Drosophila. Sun Z, et al. Genetics, 2024 Jun 5. PMID 38652268, Free PMC Article
    4. Conserved roles of Osiris genes in insect development, polymorphism and protection. Smith CR, et al. J Evol Biol, 2018 Apr. PMID 29322640
    5. Evolution of a large, conserved, and syntenic gene family in insects. Shah N, et al. G3 (Bethesda), 2012 Feb. PMID 22384409, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    osiris 23
    Names
    CG15538-PB
    Osi23-PB
    gore-tex
    osiris
    osiris23

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      30444076..30445046 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143537.3 → NP_651794.2  osiris 23 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651794.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VA75
      Conserved Domains (1) summary
      pfam07898
      Location:66 → 163
      DUF1676; Protein of unknown function (DUF1676)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VA75 Q9VA75

    Gene LinkOut

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