CG4928 uncharacterized protein [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: CG4928provided by FlyBase
Official Full Name: uncharacterized proteinprovided by FlyBase
Primary source: FLYBASE:FBgn0027556
Locus tag: Dmel_CG4928
See related: AllianceGenome:FB:FBgn0027556
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:GH10120; Dmel\CG4928
Summary: Predicted to enable potassium channel regulator activity and transmembrane transporter activity. Involved in inorganic ion homeostasis and renal system process. Predicted to be active in plasma membrane and striated muscle dense body. Is expressed in adult head. Orthologous to human UNC93A (unc-93 homolog A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: 15C1-15C4; 1-56 cM

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	X	NC_004354.4 (16913180..16938209)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	X	NC_004354.3 (16807213..16832242)

Chromosome X - NC_004354.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

mobile_element

Loc: 16936064-16936403 mobile_element_type = transposon:jockey{}145

Gene Ontology Provided by FlyBase

Function	Evidence Code	Pubs
enables potassium channel regulator activity	IBA Inferred from Biological aspect of Ancestor more info
enables transmembrane transporter activity	ISM Inferred from Sequence Model more info	PubMed

Process	Evidence Code	Pubs
involved_in inorganic ion homeostasis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of muscle contraction	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of potassium ion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in renal system process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in transmembrane transport	ISM Inferred from Sequence Model more info	PubMed

Component	Evidence Code	Pubs
is_active_in membrane	ISM Inferred from Sequence Model more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info
is_active_in striated muscle dense body	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein

Names: CG4928-PA; CG4928-PB; CG4928-PC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_004354.4 Reference assembly

Range

16913180..16938209

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_167552.2 → NP_728035.1 uncharacterized protein Dmel_CG4928, isoform A [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_728035.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0KHR6, Q6BD02, Q9Y115

UniProtKB/TrEMBL

B7Z155

Related

FBpp0074118

Conserved Domains (2) summary

cl21472
Location:49 → 155

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

cl26865
Location:255 → 426

MFS_1; Major Facilitator Superfamily
NM_132951.3 → NP_573179.1 uncharacterized protein Dmel_CG4928, isoform B [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_573179.1

Status: REVIEWED

UniProtKB/Swiss-Prot

Q0KHR6, Q6BD02, Q9Y115

UniProtKB/TrEMBL

B7Z155

Related

FBpp0074119

Conserved Domains (2) summary

cl21472
Location:49 → 155

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

cl26865
Location:255 → 426

MFS_1; Major Facilitator Superfamily
NM_001298425.1 → NP_001285354.1 uncharacterized protein Dmel_CG4928, isoform C [Drosophila melanogaster]

See identical proteins and their annotated locations for NP_001285354.1

Status: REVIEWED

UniProtKB/TrEMBL

X2JFT8

Conserved Domains (1) summary

cl21472
Location:49 → 155

MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...