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    sced scrambled [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35564, updated on 9-Dec-2024

    Summary

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    Official Symbol
    scedprovided by FlyBase
    Official Full Name
    scrambledprovided by FlyBase
    Primary source
    FLYBASE:FBgn0013732
    Locus tag
    Dmel_CG3273
    See related
    AllianceGenome:FB:FBgn0013732
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3273; CT9143; Dmel\CG3273; Sced
    Summary
    Involved in actin cytoskeleton organization and pseudocleavage involved in syncytial blastoderm formation. Colocalizes with centrosome and cleavage furrow. Is expressed in germline cell; organism; and primordial germ cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See sced in Genome Data Viewer
    Location:
    42C2-42C3; 2-55 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (6657326..6660624)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (2544831..2548129)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Optix-binding protein Neighboring gene geminin Neighboring gene DNA polymerase interacting tpr containing protein of 47kD Neighboring gene long non-coding RNA:CR45128 Neighboring gene Adh transcription factor 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Actomyosin-dependent cortical dynamics contributes to the prophase force-balance in the early Drosophila embryo. Sommi P, et al. PLoS One, 2011 Mar 31. PMID 21483831, Free PMC Article
    2. Mutations affecting the cytoskeletal organization of syncytial Drosophila embryos. Sullivan W, et al. Development, 1993 Aug. PMID 8269851
    3. The cytoskeleton and morphogenesis of the early Drosophila embryo. Sullivan W, et al. Curr Opin Cell Biol, 1995 Feb. PMID 7755985
    4. Arp2/3-dependent pseudocleavage [correction of psuedocleavage] furrow assembly in syncytial Drosophila embryos. Stevenson V, et al. Curr Biol, 2002 Apr 30. PMID 12007413
    5. Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization. Stevenson VA, et al. Nat Cell Biol, 2001 Jan. PMID 11146628

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pseudocleavage involved in syncytial blastoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    colocalizes_with centrosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with cleavage furrow IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    scrambled
    Names
    CG3273-PA
    CG3273-PB
    sced-PA
    sced-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      6657326..6660624
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136375.2 → NP_610219.2  scrambled, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610219.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NQZ5

    2. NM_001273799.1 → NP_001260728.1  scrambled, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260728.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6NQZ5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6NQZ5 Q6NQZ5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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