Taf7l TATA-box binding protein associated factor 7-like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Taf7lprovided by RGD
Official Full Name: TATA-box binding protein associated factor 7-likeprovided by RGD
Primary source: RGD:1564898
See related: EnsemblRapid:ENSRNOG00000026315 AllianceGenome:RGD:1564898
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RGD1564898
Summary: Predicted to contribute to RNA polymerase II general transcription initiation factor activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within flagellated sperm motility and spermatid development. Predicted to be located in cytoplasm and male germ cell nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF7L (TATA-box binding protein associated factor 7 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Restricted expression toward (RPKM 101.2) See more
Orthologs: human mouse all
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Genomic context

Location:: Xq32

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	X	NC_086039.1 (101953508..101968336, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	X	NC_051356.1 (97660222..97675241, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	X	NC_005120.4 (105292338..105308554, complement)

Chromosome X - NC_086039.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

TAF7L regulates early stages of male germ cell development in the rat.
Title: TAF7L regulates early stages of male germ cell development in the rat.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
contributes_to RNA polymerase II general transcription initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in RNA polymerase II preinitiation complex assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in biological_process	ND No biological Data available more info
acts_upstream_of_or_within flagellated sperm motility	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within spermatid development	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
NOT located_in chromocenter	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in male germ cell nucleus	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info
part_of transcription factor TFIID complex	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: transcription initiation factor TFIID subunit 7-like

Names: TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001434284.1 → NP_001421213.1 transcription initiation factor TFIID subunit 7-like isoform 1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000021
NM_001434285.1 → NP_001421214.1 transcription initiation factor TFIID subunit 7-like isoform 2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000021

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086039.1 Reference GRCr8

Range

101953508..101968336 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039099902.2 → XP_038955830.1 transcription initiation factor TFIID subunit 7-like isoform X1

UniProtKB/TrEMBL

A0A8I5ZWV0, A6IVF5

Related

ENSRNOP00000083355.1, ENSRNOT00000102985.2

Conserved Domains (1) summary

pfam04658
Location:123 → 302

TAFII55_N; TAFII55 protein conserved region
XM_039099903.2 → XP_038955831.1 transcription initiation factor TFIID subunit 7-like isoform X2

UniProtKB/TrEMBL

A6IVF5

Conserved Domains (1) summary

pfam04658
Location:80 → 259

TAFII55_N; TAFII55 protein conserved region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001135877.1: Suppressed sequence

Description

NM_001135877.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.