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    Kctd9 potassium channel tetramerization domain containing 9 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364410, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Kctd9provided by RGD
    Official Full Name
    potassium channel tetramerization domain containing 9provided by RGD
    Primary source
    RGD:1312010
    See related
    EnsemblRapid:ENSRNOG00000012951 AllianceGenome:RGD:1312010
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable cullin family protein binding activity and identical protein binding activity. Predicted to be involved in intracellular signal transduction and protein homooligomerization. Orthologous to human KCTD9 (potassium channel tetramerization domain containing 9). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 77.8), Thymus (RPKM 59.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Kctd9 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (46117211..46145258)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (41942165..41969862)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (44411591..44439645)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA17 Neighboring gene ribosomal protein L36, pseudogene Neighboring gene cell division cycle associated 2 Neighboring gene uncharacterized LOC103693653 Neighboring gene gonadotropin releasing hormone 1 Neighboring gene dedicator of cytokinesis 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Structural Insights into KCTD Protein Assembly and Cullin3 Recognition. Ji AX, et al. J Mol Biol, 2016 Jan 16. PMID 26334369
    2. Next-generation sequencing to generate interactome datasets. Yu H, et al. Nat Methods, 2011 Jun. PMID 21516116, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables cullin family protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein homooligomerization IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein KCTD9
    Names
    potassium channel tetramerisation domain containing 9

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108871.1 → NP_001102341.1  BTB/POZ domain-containing protein KCTD9

      See identical proteins and their annotated locations for NP_001102341.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474023
      UniProtKB/TrEMBL
      A6K6Q0, D3ZE91
      Related
      ENSRNOP00000017566.3, ENSRNOT00000017566.7
      Conserved Domains (3) summary
      COG1357
      Location:168 → 378
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd17073
      Location:2 → 66
      KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
      cd18368
      Location:89 → 188
      BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      46117211..46145258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063274490.1 → XP_063130560.1  BTB/POZ domain-containing protein KCTD9 isoform X3

      UniProtKB/TrEMBL
      A6K6Q1

    2. XM_063274488.1 → XP_063130558.1  BTB/POZ domain-containing protein KCTD9 isoform X3

      UniProtKB/TrEMBL
      A6K6Q1

    3. XM_006252142.5 → XP_006252204.1  BTB/POZ domain-containing protein KCTD9 isoform X3

      See identical proteins and their annotated locations for XP_006252204.1

      UniProtKB/TrEMBL
      A6K6Q1
      Conserved Domains (2) summary
      COG1357
      Location:54 → 264
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cl38908
      Location:1 → 74
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    4. XM_063274491.1 → XP_063130561.1  BTB/POZ domain-containing protein KCTD9 isoform X4

    5. XM_006252138.5 → XP_006252200.1  BTB/POZ domain-containing protein KCTD9 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AP15
      Conserved Domains (3) summary
      COG1357
      Location:223 → 328
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cd17073
      Location:2 → 66
      KHA; dimerization domain of potassium ion channel, similar to doublecortin-like domain, found in potassium channel tetramerization domain containing 9 (KCTD9) and similar proteins
      cd18368
      Location:89 → 188
      BTB_POZ_KCTD9; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 9 (KCTD9)

    6. XM_063274487.1 → XP_063130557.1  BTB/POZ domain-containing protein KCTD9 isoform X2

    7. XM_063274489.1 → XP_063130559.1  BTB/POZ domain-containing protein KCTD9 isoform X3

      UniProtKB/TrEMBL
      A6K6Q1

    8. XM_006252141.5 → XP_006252203.1  BTB/POZ domain-containing protein KCTD9 isoform X3

      See identical proteins and their annotated locations for XP_006252203.1

      UniProtKB/TrEMBL
      A6K6Q1
      Related
      ENSRNOP00000082382.1, ENSRNOT00000112078.2
      Conserved Domains (2) summary
      COG1357
      Location:54 → 264
      YjbI; Uncharacterized protein YjbI, contains pentapeptide repeats [Function unknown]
      cl38908
      Location:1 → 74
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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